Figure 1. Response of tick cells to challenge with heat-killed FITC-labeled JMNT Borrelia burgdorferi. Cells were fixed and stained with Evan’s blue and photographed at 50x magnification. Clusters of extracellular adherent borreliae are indicated by arrowheads. Note the withdrawn pseudopodia and borreliae coating the ISE6 cell. Unbound spirochetes can be seen in the area surrounding the ISE6 cell (arrowhead with asterisk). Scale bar 20 μm.