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Figure 9b
Fig. 9: (b) Broad structural comparison of several DPPIV proteins. DPPIV protein maps have been aligned to the conserved sequence found within the N- terminal region (DW(V/L)YEEE) that contains the double glutamic acid required for DPPIV activity (Abbott et al. 1999) This sequence is perfectly conserved except as indicated in Figure 9a. The spacing between the omega conserved sites of the N- terminal conserved sequence and catalytic triad most resembles the mammals, Aspergillus, and CG11034. The spacing of active sites for the other putative D. melanogaster DPPIV genes does not match any of the others as well. The spacing for CG3744 most closely resembles DPP9.
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