Figure 2. Generalized life cycle for species of Coelomomyces. (A) Biflagellate zygote infects hemocoel of mosquito larvae (lateral view) producing hyphagens, which later form hyphae. (B,C) Hyphae grow in the hemocoel and form resting sporangia. Occasionally, if infected (female) larvae survive to the adult stage, resting spores are formed and dispersed by 'oviposition'. Ultimately, meiospores (D) are released, which infect a copepod and produce gametophytes (E), each one of each will form gametangia (F) that release gametes of a single-mating type (G). Gametes of opposite mating type fuse inside or outside (H) copepod, forming a biflagellate zygote that completes the cycle by infecting another mosquito larva (drawn by Ernst-Jan Scholte, modified after Federici (1981)).