Table 1. Comparisons of sequence identities, lengths, molecular weights, and PIs of the GM130 subfamily proteins.

Protein Identities to Rn-GM130(%) Length (a.a.) Molecular Weight(kD) PI Overall 28 a.a. at the N-terminus 89 a.a. domain in the middle 89 a.a. domain near the C-terminus Rn-GM130         986 130* 4.86 Hs-GM130 74 100 85 91 990 130* 4.97 Ms-golgin80 16 39 26 43 708 80* 5.23 Dm-golgin90 19 57 43 45 789 90# 5.19 Ce-golgin107 15 32 33 33 937 107# 5.27 Bm-golgin107 ND ND ND 33 > 81 ND ND

Note: The identities of the three most conserved domains were compared among GM130 subfamily proteins. Amino acid number, molecular weight and PI point are also given. Abbreviations: Bm: Brugia malayi; Ce: Caenorhabditis elegans; Dm: Drosophila melanogaster; Hs: Homo sapiens; Ms: Manduca sexta; Rn: Rattus norvegicus. The sequence of Bm-golgin is based on a partial EST. The nomenclature of these molecules is described in the Results section. *: molecular weights based on estimation from Western blots; #: predictive molecular weights based on putative protein sequences; space left blank: 100% match; ND: no data available.