Figure 4. Sequence alignment of three conserved domains of the GM130 subfamily. Panel A shows the N-terminal, amino acids 1-23. Panel B shows amino acids 369-451; Panel C shows amino acids 560-648. Amino acid residues are highlighted with black blocks if at least 50% of sequence is identical. Dm-glogin90: D. melanogaster homolog derived from a Drosophila EST clone; GH01913 from a head library; genomic P1 clone DS04894; CG11061 putative protein. Ce-golgin107: C. elegans homolog from conceptual protein F33G12.5 of a hypothetical gene from the nematode genome project (Waterston and Sulston, 1995) and BM-golgin: B. malayi homolog from a 5' EST cDNA clone SW3ICA1433.