Table 3. Genes of interest in the Alate BrCA EST dataset

Gene Ontologya Sequence Identifier Accession Numberb NCBI Descriptor Source Organism E-value [p] Cellular Communication           [c] Signal transduction WHWTC-30_G08 NP_476884 14-3-3zeta; D14 3 3 protein; leonardo Drosophila melanogaster 6.00E-78   WHWTC-44_E04 NP_511144 strawberry notch; glossy-like Drosophila melanogaster 5.00E-55   WHWTC-50_D08 AAF57785 CG5036 Drosophila melanogaster 2.00E-52   WHWTC-51_F11 AAF54188 CG7918 Drosophila melanogaster 9.00E-44   WHWTC-52_H11 NP_477130 corkscrew CG3954 Drosophila melanogaster 1.00E-37   WHWTC-27_F03 O43541 Mothers against decapentaplegic homolog 6 Homo sapiens 2.00E-19   WHWTC-29_H02 AAF56349 CG7012 gene product Drosophila melanogaster 2.00E-19   WHWTC-49_B08 NP_511064 deltex Drosophila melanogaster 5.00E-15 [p] Development           [i] Cell differentiation ContigWTC[0908] NP_477122 Muscle LIM protein at 84B CG1019 Drosophila melanogaster 9.00E-50   ContigWTC[0147] AAF58567 guf gene product [alt 1] Drosophila melanogaster 4.00E-17 [i] Cell fate commitment WHWTC-09_D08 NP_523455 anterior open CG3166 Drosophila melanogaster 9.00E-51 [i] Embryonic development WHWTC-26_C07 2115375A snr1 gene Drosophila melanogaster 2.00E-38   WHWTC-01_F03 AAF49547 CG5891 gene product Drosophila melanogaster 5.00E-15 [i] Larval development ContigWTC[0852] AAF53765 CG10691 Drosophila melanogaster 2.00E-72 [i] Morphogenesis           [ii] Morphogenesis of an epithelium WHWTC-44_E08 NP_477342 discs lost CG12021 Drosophila melanogaster 3.00E-27 [ii] Organogenesis           [iii] Histogenesis           [iv] Ectoderm development ContigWTC[0527] AAF50606 CG8624 Drosophila melanogaster 3.00E-12 [iii] Imaginal disc development WHWTC-39_G11 NP_477444 COP9 complex homolog subunit 4 CG8725 Drosophila melanogaster 3.00E-10   WHWTC-41_C08 A56922 transcription factor shn Drosophila melanogaster 4.00E-22 [iii] Muscle development ContigWTC[1198] NP_477098 CG8416 Drosophila melanogaster 3.00E-98   ContigWTC[0705] A38594 troponin I Drosophila melanogaster 6.00E-53   ContigWTC[1037] AAF47158 Mlp60A gene product Drosophila melanogaster 6.00E-24 [iii] Neurogenesis WHWTC-53_E07 AAL76026 putative calreticulin Aedes aegypti 5.00E-75   ContigWTC[0118] NP_523792 FK506-binding protein 2 CG11001 Drosophila melanogaster 4.00E-40   WHWTC-28_C11 AAD03559 failed axon connections protein Drosophila virilis 4.00E-39   ContigWTC[0174] P58375 60S ribosomal protein L30 Spodoptera frugiperda 3.00E-35   ContigWTC[1050] AAF45520 CG7727 Drosophila melanogaster 4.00E-33   WHWTC-42_F10 AAD43793 CDC42 protein Drosophila melanogaster 4.00E-28   ContigWTC[0008] AAF47413 CG1007 Drosophila melanogaster 1.00E-12   WHWTC-52_E04 AAB60619 neuralized protein Drosophila virilis 3.00E-11 [iii] Trachael system development WHWTC-24_D12 AAF50772 CG10624 Drosophila melanogaster 7.00E-12 [i] Reproduction WHWTC-26_F08 XP_079633 CG5395 gene product Drosophila melanogaster 5.00E-60   WHWTC-03_C02 AAB34841 syntaxin 1, Dsynt1 Drosophila sp. 3.00E-39   WHWTC-51_A03 AAF49765 CG6451 Drosophila melanogaster 2.00E-26   WHWTC-33_F11 NP_477016 chickadee CG9553 Drosophila melanogaster 3.00E-24   ContigWTC[0744] NP_477016 chickadee CG9553 Drosophila melanogaster 5.00E-18   WHWTC-51_H09 AAF56175 CG10367 Drosophila melanogaster 2.00E-11 [p] Physiological processes           [c] Cuticle biosynthesis WHWTC-04_G08 CAC34734 Yellow protein Drosophila ananassae 3.00E-14

aAll functional assignments of Toxoptera citricida ESTs described here are the "inferred from electronic evidence" (IEA) using the top 5 BLASTX hits with an E-value of -10 generated from NCBI's nr database. The definition term associated with each sequence was entered into both FlyBase and AmiGO where the it was given a molecular function according to The Gene Ontology Consortium. bAccession numbers correspond to the "best hit" match to Genbank's nr protein database using BLASTX.