Figure 2. Comparison of the crystal structure of hvUSP LBD with the crystal structure of hsRXR and with the hvUSP hybrid homology model. -helices are represented as cylinders and -sheets as arrows. Figures were generated with Setor. (A) Superimposition of the LBD crystal structures of hsRXR in the agonist position (in light purple) and hvUSP in the antagonist position (in orange). (B) Superimposition of the hvUSP LBD crystal structure in the antagonist conformation (in orange) and hvUSP hybrid homology model in the agonist conformation (in light blue).