Figure 5b. Complete DNA and deduced amino acid sequences of the DlEPV EcoRI clone #36 (RI-36) that contains a partial open reading frame (RI-36-1) of a large gene that encodes a homolog of a DNA-directed RNA polymerase. The GenBank accession number for this sequence is AF500107. Alignment of the deduced amino acid sequences of DlEPV R1-36-1, AmEPV221, MsEPV043, and two vertebrate poxvirus homologs of Vaccinia (Vac) J6R, lumpy skin disease virus and Yaba monkey tumor virus that encode a putative DNA-directed RNA polymerase. Gold= aa shared between DlEPV and at least one of the EPV AND one of the vertebrate poxvirus sequences. Green = aa shared between DlEPV and at least one of the two entomopoxviruses, AmEPV and MsEPV, but not found in the two vertebrate poxvirus sequences; FFB6C1 Pink= EcoR1 (FE translated from the GAATTC) restriction sites; Red= aa found only in the DlEPV sequence; Shadowed area = the NADFDGDE consensus sequence of RNA polymerases; Blue = aa shared between DlEPV and at least one of the vertebrate poxvirus sequences but not found in the two EPV sequences; asterisk (*), semicolon (:) and period (.) = identical, conserved and semiconserved substitutions respectively, among all five sequences.